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HOME > News > Morigan's paper will be published in progress in biochemistry and biophysics

Morigan's papers published

Recently, the "Molecular Biology" course paper "DNA repair mechanism of RNA polymerase monitoring" by Faye Wong and Yang Yixuan (tied the first author) of the School of Life Sciences of 2017, revised under the guidance of the teacher Professor Mo Rigen It was accepted by "Progress in Biochemistry and Biophysics" and first published on CNKI. "Progress in Biochemistry and Biophysics" is an SCI-indexed by the Chinese Academy of Sciences-Biology Three Zone Journal (2020), co-sponsored by the Institute of Biophysics of the Chinese Academy of Sciences and the Chinese Biophysical Society. This article describes the DNA repair mechanism of RNA polymerase-surveilled (RNAP-S). Firstly, the mechanism of RNAP's perception of DNA damage is introduced from the structure of RNAP; secondly, the backtracking of retained RNAP, its dissociation from its template DNA, and the initiation of subsequent repair mechanisms are discussed, eukaryotic CSB and its ubiquitination and OGG1-mediated RNAP-S repair; finally, the biological significance of RNAP-S damage repair is discussed and its prospects prospect.


"Molecular Biology" is the first batch of national first-class undergraduate courses in our school, the core professional core courses of the national biology base class, and it is supported by the first-class undergraduate course construction project of Inner Mongolia University. The course focuses on implementing a problem-oriented teaching model, guiding students to find literature, read literature, and write summary papers for the frontier scientific issues raised by the teacher, and cultivate their independent thinking and problem-solving abilities to achieve innovation training. The course is explained and organized by Professor Morgen, Professor Hada, and Associate Professor Fan Life from the School of Life Sciences.



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